Tag Archives: high-dose methotrexate

Inching Toward Decisiveness

I’ve made a bit of progress on my dilemma on whether or not to go for the cranial/spinal radiation boost. This morning I ran across a study that ends like this:
“CONCLUSION: Primary chemotherapy based on high-dose MTX and ARA-C is highly efficient in PCNSL. Response rate and response duration in this series are comparable to [...]

A Big New Treatment is Approaching at Full Throttle

And as the first three methotrexate treatments went, so did the fourth. Once more I checked into the hospital on a Monday and then checked out on Thursday.
This time I wanted to do everything I could to avoid suffering through the joint pain on Saturday morning. My lizard brain considered trying to stay in the [...]

Day Two of Round Three of Volume Two

Here I am, coming to you live from Virginia Mason hospital on the second day of the third round of high-dose Methotrexate!
Last night we began the MTX infusion around 6:30 or 7pm. It finished near 11pm or midnight. I’ve had a bit more nausea this time around, but nothing so bad that we can’t stay [...]

Chemotherapy, Volume Two, Round Two B

Last Friday was my second intrathecal dose on Depocyt, and yesterday I re-admitted to the hospital to start my second round of high-dose Methotrexate. The drip finished up around 11pm, so the rescue doses of Leucovorin antidote will start up around that time.
This morning I got to be a teaching aide, too! A program coordinator [...]